Skin Booster Injections in Singapore: Types, Benefits, and What You Need to Know

fundamentalmedical
6 days ago
4 min read

Introduction

Skin booster injections have become one of the most popular aesthetic treatments in Singapore for individuals seeking refreshed, youthful, and radiant skin. Unlike dermal fillers, which add instant volume, skin boosters work beneath the surface to improve hydration, elasticity, and overall skin health.

Today, there are many different types available, ranging from the well-known hyaluronic acid skin boosters to more advanced options such as polynucleotide (PN), polydeoxyribonucleotide (PDRN), exosome-based treatments, and collagen-stimulating boosters like PLLA, PDLLA, and PCL. Understanding the differences between each can help patients choose the most suitable treatment for their skin needs.

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What Are Skin Booster Injections?

Skin boosters are injectable treatments designed to restore skin quality from within. By delivering active substances into the dermis, they trigger hydration, collagen production, and cellular repair. Unlike topical products that only work on the surface, skin booster injections penetrate deeper to activate natural regeneration. Patients who undergo these treatments often notice brighter, smoother, and firmer skin after just a few sessions.

How Do Skin Booster Treatments Work?

Skin boosters work by delivering active ingredients directly into the dermis, the deeper layer of the skin. Through micro-injections, substances such as hyaluronic acid, polynucleotides, or collagen biostimulators are evenly distributed to stimulate repair and hydration at a cellular level.

Unlike topical skincare, which only penetrates the surface, skin booster injections activate biological processes like collagen and elastin production, increased water retention, and improved cell regeneration. The result is gradual but noticeable improvement in texture, elasticity, and radiance, often after just a few sessions.

Benefits of Skin Booster Injections

The appeal of skin boosters lies in their wide range of benefits. Depending on the type of booster chosen, patients may experience:

Improved hydration → HA skin boosters deeply hydrate the skin, leaving it plump and glowing.
Scar and damage repair → PN and PDRN skin boosters repair fragile or compromised skin.
Collagen stimulation → PLLA, PDLLA, and PCL injectables restore firmness and elasticity.
Enhanced regeneration → Exosome skin boosters promote cell communication and tissue repair.
Reduction of fine lines → All boosters help soften wrinkles and improve skin texture over time.
Overall radiance → Boosters improve tone, texture, and luminosity for healthier-looking skin.

Hyaluronic Acid (HA) Skin Booster

The most widely recognised skin booster is based on hyaluronic acid (HA), a naturally occurring molecule in the body known for its ability to attract and retain water (moisturising effect). HA skin boosters are highly effective at restoring hydration, improving elasticity, and giving the skin a dewy, youthful glow. This makes them especially popular among younger patients looking for preventive anti-ageing treatments and those with dull, dehydrated skin. Examples include Restylane Skinboosters and Profhilo-type injectables.

PN and PDRN Skin Boosters

Polynucleotide (PN) and polydeoxyribonucleotide (PDRN) boosters are often grouped together but have slightly different origins. Rejuran is the best-known PDRN skin booster, derived from salmon DNA. It is particularly effective for reducing inflammation, repairing fragile skin, and stimulating collagen production for long-term rejuvenation.

Plinest, on the other hand, is a PN skin booster developed in Italy and derived from trout DNA. It has been clinically studied for its regenerative effects and is commonly recommended for patients with acne scars, ageing skin, or compromised skin barriers. Both PN and PDRN boosters belong to the same injectable family but are differentiated by their source and branding.

Exosome Skin Boosters

Exosome boosters represent a newer generation of injectable treatments. Exosomes are tiny vesicles released by cells that play a critical role in cell-to-cell communication and repair. When used in aesthetic medicine, exosome skin boosters can promote regeneration, reduce inflammation, and enhance collagen synthesis. They are often combined with treatments like microneedling or lasers for better absorption. Patients choose exosome boosters for their potential in improving skin tone, texture, and overall vitality.

PLLA Skin Booster

Poly-L-lactic acid (PLLA) is a biostimulator that gradually stimulates collagen production. Unlike HA boosters that work mainly through hydration, PLLA skin boosters work deeper to restore volume and structure over time. They are especially beneficial for patients with fine lines, wrinkles, or early sagging. Results develop gradually and are long-lasting, making PLLA a popular choice for those seeking natural but sustained rejuvenation.

Example: Sculptra-type injectables.

PDLLA Skin Booster

Poly-D,L-lactic acid (PDLLA) is another biostimulatory injectable with similar collagen-stimulating properties to PLLA, but it uses a more uniform structure to ensure consistent results. It triggers fibroblast activity, encouraging the skin to produce new collagen for a firmer, lifted appearance.

Example: Juvelook

PCL Skin Booster

Polycaprolactone (PCL) boosters are known for their long-lasting results, as they stimulate strong collagen growth while also offering some volumising effects. PCL treatments provide firmness, lift, and elasticity, making them ideal for patients with more advanced skin laxity or those seeking results that last several years.

Example: Ellansé-type injectables.

Which Skin Booster Is Right for You?

With so many different options available, the choice depends on your individual goals and skin condition.

If your main concern is hydration and glow, HA skin boosters may be best.
For skin repair and scar reduction, PN or PDRN boosters are often recommended.
Patients looking for advanced regeneration may benefit from exosome boosters.
For firmness, elasticity, and collagen stimulation, PLLA, PDLLA, or PCL injectables are excellent options.
Dry, dull skin → HA skin booster for hydration and glow.
Acne scars and fragile skin → PN (Plinest) or PDRN (Rejuran) for repair and regeneration.
Early ageing signs (fine lines, mild laxity) → HA or PN/PDRN boosters.
Moderate to severe ageing (wrinkles, sagging) → PLLA, PDLLA, or PCL boosters for collagen stimulation.
Inflamed or sensitive skin → Exosome boosters for calming and repair.

A consultation with a licensed provider in Singapore is essential to assess your skin type and recommend the most suitable treatment.

Conclusion

Skin booster injections are no longer limited to just hydration — today’s options include powerful treatments for skin repair, regeneration, and collagen stimulation. From HA to PN, PDRN, exosomes, PLLA, PDLLA, and PCL, there is a wide spectrum of solutions to suit different skin concerns. Whether you are looking to improve hydration, reduce acne scars, or restore firmness, a tailored skin booster treatment plan can help you achieve healthier, smoother, and more youthful skin.

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