Rejuran HB Plus: The Next Generation of Skin Repair and Hydration in Singapore

fundamentalmedical
3 days ago
7 min read

Introduction

In Singapore’s humid yet skin-stressing climate, maintaining firm, hydrated, and radiant skin can be a challenge. For many, traditional skin boosters provide hydration, while regenerative treatments like Rejuran Healer help repair damaged skin. But what if you could have both in one session?

Introducing Rejuran HB Plus — a breakthrough hybrid skin booster that combines Polynucleotides (PN) for skin regeneration with Hyaluronic Acid (HA) for deep hydration. As an upgraded version of previous treatments, Rejuran HB Plus offers both anti aging and water glow effect benefits, delivering enhanced skin elasticity, reduced wrinkles, and a luminous, dewy complexion. Designed for those who want smoother, plumper, and more resilient skin, this dual-action treatment has quickly become one of the most requested skin boosters in Singapore.

In this article, we’ll explore what makes Rejuran HB Plus different, how it works, its benefits—including its anti aging effect—treatment process, and why it’s gaining popularity among aesthetic patients in Singapore.

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What Is Rejuran HB Plus?

Rejuran HB Plus is part of the Rejuran family of injectables, a Korean-developed range that uses salmon DNA-based polynucleotides (PN) to rejuvenate and repair the skin at a cellular level.

The original Rejuran Healer, also known as the existing Rejuran Healer, is a foundational skin regeneration treatment derived from salmon DNA, emphasizing deep skin repair, improved elasticity, and wrinkle reduction. Unlike the traditional Rejuran Healer, which focuses primarily on skin repair and regeneration, Rejuran HB Plus is a hybrid formula that contains:

Polynucleotides (PN / PDRN) – to stimulate collagen, repair damaged skin, and improve elasticity
Hyaluronic Acid (HA) – to deeply hydrate and plump the skin
Lidocaine – to minimise injection discomfort

When comparing the respective pros of Healer and Rejuran HB, those seeking more skin regeneration effects and foundational repair may prefer the original Rejuran Healer, while patients who want enhanced hydration and a less painful experience may benefit from the upgraded HB Plus.

This combination provides both hydration and healing, making Rejuran HB Plus a powerful skin-repairing booster suitable for a wide range of skin concerns.

Clinically, the “HB” in Rejuran HB Plus stands for Hydro Booster, referring to its unique ability to improve moisture retention while repairing skin structure from within.

How Does Rejuran HB Plus Work?

Rejuran HB Plus works through a dual mechanism of action — regeneration from PN and hydration from HA. This dual mechanism supports collagen production and regenerative effects, enhancing skin elasticity and firmness.

PN (polynucleotide) is responsible for regeneration, promoting skin regeneration effects and improving skin texture by supporting the repair of damaged skin, smoothing uneven surfaces, and restoring a youthful appearance.

1. Polynucleotide (PN) for Cellular Regeneration

PN, derived from purified salmon DNA, is biocompatible with human tissue. It works by:

Stimulating fibroblast activity to boost collagen and elastin production
Improving skin barrier repair and microcirculation
Reducing inflammation and accelerating tissue healing

Research published in Clinical, Cosmetic and Investigational Dermatology (2019) found that PN injections improved skin elasticity and dermal density, confirming their regenerative effect at the dermal level.

2. Hyaluronic Acid (HA) for Deep Hydration

HA is a naturally occurring molecule that can hold up to 1,000 times its weight in water. In Rejuran HB Plus, HA acts as:

A hydrating agent, plumping and softening the skin
A support matrix, helping PN spread evenly through the dermal layers
A moisture barrier enhancer, reducing transepidermal water loss (TEWL)

This synergy between PN and HA makes Rejuran HB Plus both a healer and a hydrator, addressing multiple skin concerns simultaneously.

3. Lidocaine for Comfort

To further enhance patient comfort, the HB Plus formulation contains lidocaine, a local anesthetic that significantly reduces injection pain — an improvement over earlier Rejuran versions that often caused mild stinging during treatment.

The inclusion of lidocaine helps reduce pain and is effective in reducing pain, resulting in minimal pain during the procedure.

Benefits of Rejuran HB Plus

Rejuran HB Plus is ideal for patients who want visible improvement in overall skin health, radiance, and hydration without looking “overdone.” This treatment delivers complex effects, including deep hydration, skin regeneration, and water glow effects, resulting in a luminous and dewy complexion.

After reviewing the benefits, it’s clear that Rejuran HB Plus provides an overall anti aging effect by improving skin elasticity, hydration, and glow, making it a comprehensive solution for skin rejuvenation.

Key Benefits Include:

Category	Rejuran HB Plus Benefit
Hydration	Provides deep, long-lasting moisture retention through HA infusion
Repair & Healing	PN stimulates cellular regeneration, improving texture and tone
Skin Elasticity	Boosts collagen and elastin production for firmer, plumper skin
Radiance & Glow	Improves microcirculation and skin brightness
Comfort	Lidocaine reduces treatment discomfort significantly
Barrier Protection	Strengthens skin barrier against external stress and pollutants

💡 Clinical Insight:

A 2023 Korean study on PN + HA hybrid injectables found significant improvement in skin elasticity, wrinkle reduction, and hydration within 4 weeks, with continued improvement after 12 weeks.

Rejuran HB Plus vs Rejuran Healer: What’s the Difference?

While both belong to the Rejuran family, their formulations and focus differ slightly:

Feature	Rejuran Healer	Rejuran HB Plus
Composition	Pure Polynucleotide (PN)	PN + Hyaluronic Acid + Lidocaine
Primary Function	Skin regeneration	Skin repair + hydration
Injection Sensation	Mild to moderate discomfort	Gentler due to lidocaine
Texture Effect	Firmer, smoother skin over time	Hydrated, plumper, dewier skin
Best For	Damaged, ageing, or acne-scarred skin	Dry, dull, or dehydrated skin needing both repair and glow

In short: Rejuran Healer repairs; Rejuran HB Plus repairs and hydrates. Many practitioners recommend receiving Rejuran HB Plus for those seeking an upgraded version of the treatment, as it offers reduced pain, enhanced hydration, and a water glow effect. If you want a less painful procedure with both skin regeneration and glow, experts often recommend Rejuran HB.

Who Is Suitable for Rejuran HB Plus?

Rejuran HB Plus is suitable for both men and women who want to improve their skin texture and hydration without resorting to heavy fillers or aggressive laser procedures.

Ideal candidates include those with:

Dull or dehydrated skin
Fine lines and early wrinkles
Uneven texture or mild pigmentation
Post-acne marks or early scarring
Aging concerns such as wrinkles, loss of elasticity, or collagen depletion
Acne scars and uneven skin texture
Sensitive or thin skin prone to dryness

Rejuran HB Plus is also suitable for individuals with sensitive skin and those experiencing various skin problems, such as dryness, flakiness, or skin weakness.

It’s also popular among patients who found Rejuran Healer too “drying” or uncomfortable, but still want the regenerative benefits.

To maximize results, proper self care before and after treatment is essential.

Treatment Process

A typical Rejuran HB Plus treatment in Singapore follows these steps:

Consultation – The doctor assesses your skin and explains expected outcomes.
Cleansing & Numbing – Skin is cleaned, and a topical anesthetic cream is applied for 20–30 minutes.
Injection – The Rejuran HB Plus is injected into the dermis using fine micro-needles or a mesotherapy gun.
Post-treatment – A soothing mask or LED therapy may be used to calm the skin and enhance absorption.
Recovery – Small injection bumps and mild redness, known as the embossing process, typically subside within 24–48 hours.

A typical treatment cycle consists of 3–4 sessions spaced 3–4 weeks apart for optimal results.

Most patients can return to their daily life immediately after treatment.

📅 Recommended Protocol:

Initial course: 3–4 sessions, spaced 3–4 weeks apart
Maintenance: Every 6–9 months

Treatment Options and Areas

At Fundamental Aesthetic Clinic, we understand that every individual’s skin is unique, which is why we offer a range of Rejuran HB Plus treatment options tailored to your specific needs. Whether you’re looking to restore overall skin balance, enhance elasticity, or boost hydration, our expert team can target key areas of the face—including the forehead, cheeks, under-eye region, and jawline—to deliver visible, natural-looking results.

Each Rejuran HB Plus session is carefully designed to address your skin’s unique concerns, helping to strengthen thin or damaged skin, smooth out uneven texture, and restore moisture balance. By focusing on both hydration and skin repair, our treatments work to improve overall skin balance and resilience, leaving your complexion looking more youthful, radiant, and refreshed.

With the advanced formulation of Rejuran HB Plus, you can expect not only enhanced skin elasticity and hydration, but also a noticeable improvement in the overall appearance and texture of your skin. Our personalized approach ensures that every treatment supports your journey to healthier, more youthful-looking skin—so you can feel confident in your appearance every day.

Aftercare Tips

To ensure optimal results, patients should follow these guidelines after each session:

Avoid makeup, alcohol, and strenuous exercise for 24 hours
Avoid laser or chemical peels for one week
Keep skin moisturised and protected with SPF
Use gentle, non-active skincare products

Redness and swelling are normal for 1–2 days, with full results visible after about 2–4 weeks as collagen synthesis increases.

Results & Longevity

Initial results: within 2–3 weeks (hydration and glow)
Full results: at 4–6 weeks (firmer, smoother, healthier skin)
Longevity: 6–9 months, extendable with regular maintenance

Clinical observations show that PN + HA hybrid boosters like Rejuran HB Plus can help reduce fine lines, refine pores, and improve skin barrier integrity with consistent sessions.

Safety and Possible Side Effects

Rejuran HB Plus is considered safe and biocompatible, as its ingredients are purified and naturally occurring in the body. Possible side effects include:

Mild redness or swelling
Small papules at injection sites
Temporary tenderness or bruising

Serious reactions are extremely rare, especially when administered by experienced, MOH-licensed medical practitioners in Singapore.

Why Rejuran HB Plus Is Popular in Singapore

Singapore’s aesthetic market is seeing a shift toward multi-functional skin boosters — treatments that provide more than just hydration.

Rejuran HB Plus fits this trend perfectly by combining:

✅ Regenerative science (PN)

✅ Hydrating technology (HA)

✅ Comfort (Lidocaine)

It appeals to patients who want subtle, natural improvements rather than drastic changes.

Related Treatments

Rejuran HB Plus can be safely combined with other aesthetic procedures to enhance results:

PDRN Skin Repair Treatments – for deeper regeneration
HA Skin Boosters – for hydration layering
Laser or RF Microneedling – to target scars or laxity
Exosome Skin Therapy – to boost healing response

Your doctor can create a custom treatment plan that layers therapies for optimal rejuvenation and glow.

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