Pico Laser vs Rejuran: Understanding the Differences
- fundamentalmedical
- Sep 11
- 3 min read
Introduction
When it comes to non-surgical skin treatments, two popular options are Pico Laser and Rejuran. Both address skin concerns such as pigmentation, scars and signs of aging but they work differently. Knowing how each treatment works, what they target and their long term effects will help you make an informed decision.
What is Pico Laser?
Pico Laser is a laser treatment that delivers ultra short pulses of energy into the skin. The pulses measured in picoseconds break down unwanted pigmentation, target tattoo ink and stimulate collagen production. Because the energy is delivered in extremely short bursts, there is minimal heat damage to surrounding tissue.
This makes Pico Laser suitable for:
Pigmentation issues
Acne scars
Uneven skin tone
Fine lines
Tattoo removal
What is Rejuran?
Rejuran is an injectable treatment made from polynucleotides (PN) which are DNA fragments derived from salmon. It works by stimulating skin repair at a cellular level, improving skin texture, elasticity and hydration. Instead of breaking down pigmentation or scar tissue, Rejuran enhances the skin’s natural healing process.
Common uses for Rejuran:
Fine lines and wrinkles
Enlarged pores
Skin elasticity and hydration
Overall skin rejuvenation
Pico Laser vs Rejuran: Key Differences
Feature | Pico Laser | Rejuran |
Mechanism & Application | Uses ultra short laser pulses to break down pigmentation and stimulate collagen production. | Micro-injections of polynucleotides to promote skin repair, hydration and elasticity. |
Main Purpose / Best For | Targets pigmentation, acne scars, uneven skin tone, fine lines and tattoos. | Improves skin texture, elasticity, hydration, fine lines, sagging skin, dullness and enlarged pores. |
Downtime & Side Effects | Mild redness or swelling, usually resolves within hours to a day. | Small bumps at injection sites, typically settles within a few days. |
Results Timeline & Longevity | Multiple sessions required; visible results after a few treatments. | Gradual results over weeks; cumulative benefits from repeated sessions. |
Heat Effect & Safety | Minimal thermal damage due to ultra short pulses; suitable for most skin types. | No heat involved; promotes cellular repair; generally safe for most skin types. |
Method of Application
Pico Laser: Uses targeted light energy to break down pigmentation and stimulate collagen.
Rejuran: Involves micro-injections of polynucleotides directly into the skin.
Main Treatment Focus
Pico Laser: More effective for pigmentation, acne scars, and tattoo removal.
Rejuran: More suitable for skin healing, hydration, and anti-aging purposes.
Downtime and Recovery
Pico Laser: Usually involves mild redness or swelling that fades within hours to a day.
Rejuran: May cause small bumps at injection sites that settle within a few days.
Longevity of Results
Pico Laser: Results depend on skin condition and aftercare, often requiring multiple sessions.
Rejuran: Gradual improvements over several weeks, with multiple sessions recommended for sustained effects.
Can pico laser and rejuran be done at the same sesssion?
Yes, pico laser and Rejuran can be performed in the same session, as they complement each other—pico laser targets surface concerns like pigmentation and acne scars, while Rejuran’s polynucleotides support collagen production and skin repair from within. Combining them can improve overall skin quality, including tone, elasticity, and firmness, offering more comprehensive rejuvenation than either treatment alone. A qualified professional should assess suitability and adjust techniques for safe and effective results.
Cost price for Pico laser and Rejuran
In Singapore, Pico Laser treatments generally cost between S$150 and S$250 per session, depending on the treatment area, number of sessions, and skin condition. Rejuran treatments typically range from S$350 to over S$1,000 per session, influenced by the i treatment area, and the specific Rejuran formulation, with full-face sessions often requiring 2–3 syringes.
Which One is More Suitable?
The choice between Pico Laser vs Rejuran depends on the skin concern. For pigmentation, scars and uneven tone, Pico Laser is more effective. For skin elasticity, hydration and overall rejuvenation, Rejuran is more suitable. In some cases, both can be used together but this should be guided by certified MOH aesthetic doctor assessment.
Considerations Before Treatment
Before choosing between Pico Laser and Rejuran, skin type, medical history and desired outcome should be evaluated. Individuals with skin sensitivities, underlying conditions or specific goals may find one more suitable than the other. A proper consultation is essential for safe and effective results.
Conclusion
When comparing Pico Laser vs Rejuran, the main difference is in their mechanism and treatment goals. Pico Laser uses laser energy to target pigmentation and scars while Rejuran uses polynucleotides to repair and rejuvenate skin from within. Knowing how each works will give you clarity on non-invasive options to improve skin health.
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