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Plinest (PN) vs Profhilo (HA): Which Skin Booster Treatment is Better for You in Singapore?

Skin booster injections have become one of the most popular aesthetic treatments in Singapore, especially for individuals looking to restore hydration, improve skin texture, and slow down signs of ageing (fine lines and wrinkles) — without surgery.


Two well-known options are Plinest Singapore (polynucleotide skin repair treatment) and Profhilo Singapore (hyaluronic acid skin hydration treatment). While both belong to the family of injectable skin booster treatments, they work in different ways and are suited for different skin concerns. Understanding their differences will help you choose the treatment that best fits your needs.

What Are Skin Boosters?


Skin boosters are injectable treatments designed to improve overall skin quality by delivering substances such as hyaluronic acid (HA) or polynucleotides (PN) directly into the skin. Unlike dermal fillers, which add volume or reshape facial contours, skin boosters focus on skin health, hydration, and repair.


They are popular in Singapore because they:

  • Improve hydration for dull, dry skin

  • Stimulate collagen production for anti-ageing benefits

  • Repair damaged or scarred skin

  • Enhance the skin’s elasticity, glow, and resilience


Types of Skin Boosters in Singapore


  1. Hyaluronic Acid (HA) Skin Boosters

    • Known for deep hydration and improved elasticity

    • Popular among patients with dry or sagging skin

    • Example: HA skin hydration treatment


  2. Polynucleotide (PN) Skin Boosters

    • Focus on repairing damaged skin and stimulating regeneration

    • Ideal for acne scars, sensitive skin, and anti-ageing repair

    • Example: PN skin repair treatment


  3. Collagen Stimulators

    • Encourage the body to produce new collagen gradually

    • Improve volume loss, firmness, and long-term skin health

    • Example: PLLA-based injectables like collagen biostimulators


With a better understanding of what skin boosters are and the main types available, let’s take a closer look at Plinest (PN skin repair treatment) and Profhilo (HA skin hydration treatment) — two of the most popular options in Singapore.

What is Polynucleotide Skin Repair Treatment?


Plinest, also known as a PN skin booster, is made from purified DNA fragments derived from natural sources. These polynucleotides are known for their ability to support cell regeneration, tissue healing, and collagen production.


Plinest aka PN skin repair inection

How it works

  • Repairs damaged skin cells and strengthens the skin barrier

  • Stimulates collagen and elastin production for long-term results

  • Reduces inflammation, making it suitable for sensitive skin


Benefits of PN Skin Repair Treatment

  • Acne scars: Helps smoothen and repair scarred skin

  • Skin sensitivity: Strengthens fragile or compromised skin

  • Fine lines: Softens early wrinkles by boosting collagen

  • Skin texture: Improves uneven tone and enlarged pores


Unlike hydrating injectables that show quick glow, the PN treatment is more progressive, with benefits becoming clearer over several weeks as the skin repairs itself naturally.

What is Hyaluronic Acid Skin Hydration Treatment?


Profhilo belongs to the hyaluronic acid (HA) skin booster group. Hyaluronic acid is a naturally occurring substance in the body that retains water and keeps the skin plump. With ageing, HA levels decline, leading to dryness, dullness, and sagging.


Profhilo aka HA skin hydration

How it works

  • Injects concentrated hyaluronic acid beneath the skin

  • Attracts and holds water molecules for deep hydration

  • Spreads evenly to improve elasticity and firmness


Benefits of HA Skin Hydration Treatment

  • Deep hydration: Restores moisture for dewy, glowing skin

  • Elasticity: Improves skin bounce and firmness

  • Fine lines: Reduces small wrinkles caused by dehydration

  • Skin glow: Restores radiance to dull, tired-looking skin


Results are usually visible faster compared to PN-based treatments, often within 1–2 weeks, making it a favourite for those seeking quick improvements.

PN vs HA: Side-by-Side Comparison

Feature

PN Skin Repair Treatment

HA Skin Hydration Treatment

Main focus

Repair, regeneration, barrier strength

Hydration, elasticity, glow

Best for

Acne scars, sensitive skin, ageing

Dehydrated, dull, sagging skin

Results timeline

Gradual, progressive over weeks

Faster, often visible in 1–2 weeks

Longevity

Long-term improvement with collagen regeneration

6–9 months of hydration & firmness

Mechanism

Stimulates cell repair & collagen production

Retains water & improves skin density

Skin type match

Damaged, sensitive, or scarred skin

Dry, dull, or ageing skin needing moisture

Which Treatment Should You Choose?


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  • Go for PN skin repair treatments if:

    • You want to target acne scars, sensitivity, or skin damage

    • You prefer treatments that strengthen and regenerate skin long-term


  • Go for HA skin hydration treatments if:

    • Your main concern is dryness, dullness, or loss of elasticity

    • You want fast results with visible glow and firmness


Some patients benefit from a combination approach, where both treatments are used in a customised plan. This provides hydration, repair, and anti-ageing benefits together. Always consult a qualified doctor to decide what’s right for your skin.

Safety and Downtime


Both PN and HA skin boosters are considered safe and minimally invasive.

  • Downtime: Mild redness, swelling, or tiny bumps may appear at injection sites, usually resolving within 24–48 hours.

  • Comfort: Numbing cream is applied before treatment to reduce discomfort.

  • Safety: Treatments are suitable for most skin types but should be performed by licensed professionals in a medical clinic setting.

Conclusion


Both PN skin repair treatment and HA skin hydration treatment are effective options for improving skin quality in Singapore. The best choice depends on your skin concerns: whether it’s acne scars and sensitivity (PN) or hydration and elasticity (HA).


Whichever you choose, both treatments offer a non-surgical way to rejuvenate your skin, helping you look refreshed, radiant, and confident.



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